The now iconic 'How do you do, fellow kids?' meme spawns from a season 6 episode of 30 Rock.
In it, the then 55-year-old actor dresses up as your typical '90s teen in a scene for a show parodying 21 Jump Street, with Buscemi's character going undercover at a high school.
Since then, though, the scene took on even greater significance as a reaction meme, typically used when a person feels out of place due to their age.
Obviously, Buscemi is well aware of his position as one of the internet's favorite memes and took things one step further by recreating the outfit for Halloween.